Tyrosine yog qhov tseem ceeb tseem ceeb aminocarboxylic acid koom nrog catabolism thiab anabolism, suav nrog kev sib txuas ntawm cov leeg protein, dopamine, thiab neurotransmitters. Tsim los ntawm phenylalanine.
Tyrosine synthesis mechanism
Cov mis muaj txiaj ntsig ntawm tyrosine yog C₉H₁₁NO₃, phenylalanine yog C₉H₁₁NO₂. Tyrosine yog tsim raws li cov txheej txheem hauv qab no:
C₉H₁₁NO₂ + phenylalanine-4-hydroxylase => C₉H₁₁NO₃.
Cov kev mob lom hauv lub cev ntawm tyrosine
Yuav ua li cas tyrosine cuam tshuam rau lub cev thiab cov haujlwm uas nws ua:
- ua cov khoom siv yas ua kev tsim cov melanin, catecholamine hormones los yog catecholamines (adrenaline thiab norepinephrine, dopamine, thyroxine, triiodothyronine, L-dioxyphenalalanine), neurotransmitters thiab neurotransmitters;
- siv txoj hauv kev ua haujlwm ntawm cov thyroid thiab cov qog adrenal;
- txhim kho kev ua siab ntev thaum muaj kev ntxhov siab, txhawb nqa kev rov ua haujlwm qub;
- muaj qhov cuam tshuam zoo ntawm kev ua haujlwm ntawm lub paj hlwb thiab cov twj siv vestibular;
- pom zoo detoxification;
- ua pov thawj kev tawm tsam;
- nce hlwb kev xav;
- koom nrog kev hloov pauv kub;
- suppresses catabolism;
- relieves cov tsos mob ntawm tus mob premenstrual syndrome.
Kev siv cov tyrosine rau poob phaus
Vim nws lub peev xwm los txhim kho kev siv cov rog, L-tyrosine siv thaum lub sijhawm ziab (yuag poob) raws li kev saib xyuas ntawm tus kws kho mob kis las.
Yuav siv ntau npaum li cas tyrosine ib hnub
Cov koob tshuaj txhua hnub ntawm tyrosine nyob ntawm 0.5-1.5 grams, nyob ntawm seb puas siab puas ntsws-kev xav thiab lub cev. Noj tshuaj amino acid rau ntau dua 3 lub hlis sib law liag tsis pom zoo. Nws yog qhov zoo tshaj rau haus nrog zaub mov nrog dej me me.
Txhawm rau txhim kho txoj kev kho kom zoo, tyrosine raug pom zoo kom siv ua ke nrog methionine thiab vitamins B6, B1 thiab C.
Tsis muaj thiab dhau ntawm cov tyrosine, cov cim thiab cov txim ntsig
Ib qho dhau heev lawm (hypertyrosinosis lossis hypertyrosinia) lossis ib qho tsis txaus (hypothyrosinia lossis hypothyrosinosis) ntawm cov amino acid tyrosine hauv lub cev tuaj yeem ua rau lub cev tsis tuaj yeem cuam tshuam txog metabolic.
Cov tsos mob ntau dhau thiab tsis muaj tus mob tyrosine yog qhov tsis muaj tseeb, uas ua rau kev kuaj pom nyuaj. Thaum ua qhov kev kuaj mob, nws yog ib qho tseem ceeb uas yuav tsum tau coj mus rau hauv cov ntaub ntawv anamnestic (pauv ntawm lub sijhawm ua ntej ntawm tus kabmob, noj tshuaj, ua rau noj zaub mov noj).
Tshaj
Ib qho dhau heev ntawm tyrosine tuaj yeem tshwm sim nws tus kheej tias yog kev tsis txaus hauv kev ua haujlwm:
- cov qog adrenal;
- nruab nrab thiab ntu ntu paj hlwb;
- cov ua cov thyroid caj pas (hypothyroidism).
Nyias tsis zoo
Amino acid deficiency yog cov cim hauv qab no:
- nce kev ua si rau menyuam yaus;
- txo qis ntshav siab (ntshav siab);
- txo qis hauv lub cev kub;
- kev txwv tsis pub tawm dag zog thiab lub hlwb hauv cov laus;
- leeg tsis muaj zog;
- kev nyuaj siab;
- mus ob peb vas hloov pauv;
- hnyav nce nrog cov khoom noj tsis tu ncua;
- nyob tsis tswm ceg syndrome;
- plaub hau poob;
- nce pw tsaug zog;
- tsis qab los.
Qhov tsis txaus ntawm tyrosine tuaj yeem tshwm sim los ntawm qhov tsis muaj nws cov khoom noj nrog zaub mov lossis tsim tsis txaus los ntawm phenylalanine.
Hypertyrosinosis yog tus cwj pwm hauv qee qhov los ntawm kev muaj zog zuj zus ntawm thyroxine ntau lawm (Cov kab mob Graves):
- ib qho kev ceeb toom txo tau hauv lub cev hnyav;
- kev pw tsaug zog;
- nce excitability;
- kiv taub hau;
- mob taub hau;
- tachycardia;
- Cov tsos mob dyspeptic (tsis muaj qab los noj mov, xeev siab, kub siab, ntuav, nce acidity ntawm lub plab zom mov, hyperacid gastritis lossis mob plab hnyuv lossis duodenal mob).
Cov Yuav Tsum Tau Ua
Kev npaj Tyrosine tsis pom zoo rau siv nrog:
- intolerance lossis tsis haum tshuaj rau cov khoom xyaw lossis tshuaj ntxiv;
- kab mob ntawm cov thyroid caj pas (hyperthyroidism);
- kev mob hlwb (kab mob schizophrenia);
- mob muaj keeb tyrosinemia;
- kev kho mob nrog MAO (monoamine oxidase) inhibitors;
- Parkinson tus mob.
Sab sij huam
Cov kev mob tshwm sim muaj ntau yam thiab txiav txim siab tsis yog los ntawm qee tus yam ntxwv ntawm ib tug neeg, tab sis kuj los ntawm ntau cov kev hloov hauv cov tshuaj biochemical uas aminocarboxylic acid siv. Hauv qhov no, txhawm rau tiv thaiv lawv, nws raug nquahu kom pib noj cov amino acid nrog kev noj tshuaj tsawg kawg hauv qab kev saib xyuas ntawm tus kws kho mob koom.
Cov kev mob tshwm sim feem ntau suav nrog kev mob caj dab, mob taub hau, kub siab, thiab xeev siab.
Kev sib txuam
Ib qho kev hloov hauv cov nyhuv pharmacological ntawm tyrosine tsis cais tawm thaum siv ua ke nrog haus dej cawv, opiates, tshuaj steroids lossis cov tshuaj ntaus pob ncaws pob. Hauv qhov no, nws raug nquahu kom nce cov tshuaj uas maj mam dhau los txhawm rau tshem tawm ib qho kev sib txuam uas tsis tsim nyog yog tias tsim nyog.
Tyrosine-nplua nuj cov zaub mov
Cov amino acid muaj nyob hauv cov nqaij ntawm cov tsiaj, cov noog thiab ntses, taum pauv, txiv laum huab xeeb, khoom noj siv mis, taum pauv, hom qoob mog, oatmeal, nqaij nruab deg, zaub mov ntxiv.
Khoom npe | Tyrosine hnyav hauv grams tauj 100 g ntawm cov khoom |
Nqaij ntau yam | 0,34-1,18 |
Ob txhais ceg | 0,10-1,06 |
Cereals | 0,07-0,41 |
Ceev | 0,51-1,05 |
Khoom noj siv mis | 0,11-1,35 |
Zaub | 0,02-0,09 |
Txiv hmab txiv ntoo thiab berries | 0,01-0,10 |
Kev noj zaub mov kis las nrog L-tyrosine
L-Tyrosine muaj nyob rau hauv 1100 mg ntsiav tshuaj thiab 400 mg, 500 mg lossis 600 mg tsiav tshuaj. 1 lub thawv yas muaj 60 ntsiav tshuaj, lossis 50, 60 lossis 100 tsiav tshuaj. Microcrystalline cellulose, aerosil thiab Mg stearate yog siv los ua cov muab tub lim.
Tus nqi hauv lub khw muag tshuaj rau 60 qhov kev xav tau ntawm 500 mg yog nyob rau hauv thaj tsam ntawm 900-1300 rubles.
Daim ntawv thov thiab koob tshuaj
Qhov nruab nrab txhua hnub xav tau rau tyrosine rau ib tus neeg laus yog 25 mg / kg (1.75 g / hnub). Cov koob tshuaj tuaj yeem sib txawv raws li lub hom phiaj ntawm kev siv tshuaj (xaiv los ntawm tus kws kho mob koom nrog).
Dosage nyob rau hauv grams | Ntau yam ntawm kev txais tos | Lub sijhawm nkag | Cov tsos mob, tus mob syndrome lossis daim ntawv nosological | Lus khaws xav |
0,5-1,0 | 3 zaug ib hnub | 12 lub lis piam | Kev Nyuaj Siab | Xws li cov tshuaj tiv thaiv kab mob me |
0,5 | Insomnia | – | ||
5,0 | Tas li | Phenylketonuria | – |
Nws raug nquahu kom dilute khoom nrog tyrosine hauv cov kua lossis kua txiv kab ntxwv.